2hro
From Proteopedia
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| - | [[Image:2hro.png|left|200px]] | ||
| - | + | ==Structure of the full-lenght Enzyme I of the PTS system from Staphylococcus carnosus== | |
| - | + | <StructureSection load='2hro' size='340' side='right'caption='[[2hro]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2hro]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_carnosus Staphylococcus carnosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HRO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hro OCA], [https://pdbe.org/2hro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hro RCSB], [https://www.ebi.ac.uk/pdbsum/2hro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hro ProSAT]</span></td></tr> |
| - | [[2hro]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PT1_STACT PT1_STACT] General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hr/2hro_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hro ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Phosphotransferase|Phosphotransferase]] | + | *[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | |
[[Category: Staphylococcus carnosus]] | [[Category: Staphylococcus carnosus]] | ||
| - | [[Category: Engelman | + | [[Category: Engelman R]] |
| - | [[Category: Hengstenberg | + | [[Category: Hengstenberg W]] |
| - | [[Category: Koch | + | [[Category: Koch B]] |
| - | [[Category: Marquez | + | [[Category: Marquez JA]] |
| - | [[Category: Reinelt | + | [[Category: Reinelt S]] |
| - | [[Category: Scheffzek | + | [[Category: Scheffzek K]] |
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Current revision
Structure of the full-lenght Enzyme I of the PTS system from Staphylococcus carnosus
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