2krc

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[[Image:2krc.png|left|200px]]
 
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{{STRUCTURE_2krc| PDB=2krc | SCENE= }}
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==Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase==
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<StructureSection load='2krc' size='340' side='right'caption='[[2krc]]' scene=''>
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===Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2krc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krc OCA], [https://pdbe.org/2krc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krc RCSB], [https://www.ebi.ac.uk/pdbsum/2krc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krc ProSAT]</span></td></tr>
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[[2krc]] is a 1 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRC OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPOE_BACSU RPOE_BACSU] Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling. May function in sigma factor switching. It displaces RNA bound to RNA polymerase in a binary complex.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2krc ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020310067</ref><references group="xtra"/>
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Jonak, J.]]
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[[Category: Large Structures]]
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[[Category: Krasny, L.]]
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[[Category: Jonak J]]
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[[Category: Motackova, V.]]
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[[Category: Krasny L]]
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[[Category: Novacek, J.]]
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[[Category: Motackova V]]
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[[Category: Padrta, P.]]
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[[Category: Novacek J]]
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[[Category: Sanderova, H.]]
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[[Category: Padrta P]]
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[[Category: Sklenar, V.]]
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[[Category: Sanderova H]]
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[[Category: Svenkova, A.]]
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[[Category: Sklenar V]]
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[[Category: Zidek, L.]]
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[[Category: Svenkova A]]
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[[Category: Delta subunit]]
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[[Category: Zidek L]]
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[[Category: Dna-directed rna polymerase]]
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[[Category: Gram-positive bacteria]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Rna polymerase]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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Current revision

Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase

PDB ID 2krc

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