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2hnx

From Proteopedia

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[[Image:2hnx.png|left|200px]]
 
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{{STRUCTURE_2hnx| PDB=2hnx | SCENE= }}
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==Crystal Structure of aP2==
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<StructureSection load='2hnx' size='340' side='right'caption='[[2hnx]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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===Crystal Structure of aP2===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2hnx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HNX FirstGlance]. <br>
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{{ABSTRACT_PUBMED_17077479}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hnx OCA], [https://pdbe.org/2hnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hnx RCSB], [https://www.ebi.ac.uk/pdbsum/2hnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hnx ProSAT]</span></td></tr>
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[[2hnx]] is a 1 chain structure of [[Fatty acid-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HNX OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hn/2hnx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hnx ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Fatty acid-binding protein|Fatty acid-binding protein]]
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*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:017077479</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Carty, M.]]
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[[Category: Large Structures]]
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[[Category: Karam, G.]]
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[[Category: Brown Phillips T]]
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[[Category: Marr, E.]]
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[[Category: Carty M]]
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[[Category: Phillips, T Brown.]]
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[[Category: Karam G]]
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[[Category: Qiu, X.]]
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[[Category: Marr E]]
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[[Category: Tardie, M.]]
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[[Category: Qiu X]]
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[[Category: Fatty acid binding protein]]
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[[Category: Tardie M]]
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[[Category: Lipid binding protein]]
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Current revision

Crystal Structure of aP2

PDB ID 2hnx

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