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2fyo

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[[Image:2fyo.png|left|200px]]
 
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{{STRUCTURE_2fyo| PDB=2fyo | SCENE= }}
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==Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212==
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<StructureSection load='2fyo' size='340' side='right'caption='[[2fyo]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fyo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FYO FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyo OCA], [https://pdbe.org/2fyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fyo RCSB], [https://www.ebi.ac.uk/pdbsum/2fyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fyo ProSAT]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fy/2fyo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fyo ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.
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===Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212===
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A monotopic membrane protein goes solo.,Mattevi A Structure. 2006 Apr;14(4):628-9. PMID:16615901<ref>PMID:16615901</ref>
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{{ABSTRACT_PUBMED_16615901}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 2fyo" style="background-color:#fffaf0;"></div>
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[[2fyo]] is a 1 chain structure of [[Carnitine palmitoyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYO OCA].
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==See Also==
==See Also==
*[[Carnitine palmitoyltransferase|Carnitine palmitoyltransferase]]
*[[Carnitine palmitoyltransferase|Carnitine palmitoyltransferase]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:016615901</ref><ref group="xtra">PMID:016615913</ref><references group="xtra"/>
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__TOC__
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[[Category: Carnitine O-palmitoyltransferase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Banner, D W.]]
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[[Category: Banner DW]]
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[[Category: Benz, J.]]
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[[Category: Benz J]]
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[[Category: Chomienne, O.]]
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[[Category: Chomienne O]]
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[[Category: Gsell, B.]]
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[[Category: De Roo E]]
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[[Category: Hennig, M.]]
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[[Category: Gsell B]]
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[[Category: Mueller, F.]]
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[[Category: Hennig M]]
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[[Category: Roo, E De.]]
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[[Category: Mueller F]]
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[[Category: Rufer, A C.]]
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[[Category: Rufer AC]]
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[[Category: Stihle, M.]]
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[[Category: Stihle M]]
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[[Category: Thoma, R.]]
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[[Category: Thoma R]]
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[[Category: Central six-stranded beta-sheet]]
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[[Category: Transferase]]
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Current revision

Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212

PDB ID 2fyo

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