1bg8
From Proteopedia
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| - | [[Image:1bg8.gif|left|200px]]<br /><applet load="1bg8" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1bg8, resolution 2.2Å" /> | ||
| - | '''HDEA FROM ESCHERICHIA COLI'''<br /> | ||
| - | == | + | ==HDEA FROM ESCHERICHIA COLI== |
| - | + | <StructureSection load='1bg8' size='340' side='right'caption='[[1bg8]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1bg8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BG8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BG8 FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bg8 OCA], [https://pdbe.org/1bg8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bg8 RCSB], [https://www.ebi.ac.uk/pdbsum/1bg8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bg8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HDEA_ECOLI HDEA_ECOLI] Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA.<ref>PMID:15911614</ref> <ref>PMID:17085547</ref> <ref>PMID:18359765</ref> <ref>PMID:21892184</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Boyd | + | [[Category: Boyd MR]] |
| - | [[Category: Gustafson | + | [[Category: Gustafson KR]] |
| - | [[Category: Wlodawer | + | [[Category: Wlodawer A]] |
| - | [[Category: Yang | + | [[Category: Yang F]] |
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Current revision
HDEA FROM ESCHERICHIA COLI
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