1plq

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[[Image:1plq.png|left|200px]]
 
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{{STRUCTURE_1plq| PDB=1plq | SCENE= }}
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==CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA==
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<StructureSection load='1plq' size='340' side='right'caption='[[1plq]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1plq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PLQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PLQ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8001157}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1plq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1plq OCA], [https://pdbe.org/1plq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1plq RCSB], [https://www.ebi.ac.uk/pdbsum/1plq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1plq ProSAT]</span></td></tr>
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[[1plq]] is a 1 chain structure of [[Proliferating Cell Nuclear Antigen]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PLQ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PCNA_YEAST PCNA_YEAST] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.<ref>PMID:11545742</ref> <ref>PMID:12226657</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pl/1plq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1plq ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Proliferating Cell Nuclear Antigen|Proliferating Cell Nuclear Antigen]]
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*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:008001157</ref><ref group="xtra">PMID:011266590</ref><ref group="xtra">PMID:011742118</ref><ref group="xtra">PMID:016955075</ref><ref group="xtra">PMID:019053247</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Burgers, P M.]]
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[[Category: Burgers PM]]
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[[Category: Gary, S.]]
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[[Category: Gary S]]
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[[Category: Kong, X P.]]
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[[Category: Kong X-P]]
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[[Category: Krishna, T S.R.]]
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[[Category: Krishna TSR]]
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[[Category: Kuriyan, J.]]
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[[Category: Kuriyan J]]
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[[Category: Dna replication]]
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[[Category: Dna-binding]]
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[[Category: Nuclear protein]]
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[[Category: Processivity factor]]
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Current revision

CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA

PDB ID 1plq

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