1f0x

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[[Image:1f0x.png|left|200px]]
 
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{{STRUCTURE_1f0x| PDB=1f0x | SCENE= }}
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==CRYSTAL STRUCTURE OF D-LACTATE DEHYDROGENASE, A PERIPHERAL MEMBRANE RESPIRATORY ENZYME.==
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<StructureSection load='1f0x' size='340' side='right'caption='[[1f0x]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF D-LACTATE DEHYDROGENASE, A PERIPHERAL MEMBRANE RESPIRATORY ENZYME.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1f0x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F0X FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10944213}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f0x OCA], [https://pdbe.org/1f0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f0x RCSB], [https://www.ebi.ac.uk/pdbsum/1f0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f0x ProSAT]</span></td></tr>
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[[1f0x]] is a 2 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F0X OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DLD_ECOLI DLD_ECOLI] First component of the membrane-bound D-lactate oxidase, which is believed to play an important role in the energization of the active transport of a variety of sugars and amino acids.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/1f0x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f0x ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010944213</ref><references group="xtra"/>
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[[Category: D-lactate dehydrogenase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Dym, O.]]
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[[Category: Large Structures]]
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[[Category: Eisenberg, D.]]
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[[Category: Dym O]]
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[[Category: Ho, C.]]
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[[Category: Eisenberg D]]
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[[Category: Pratt, E A.]]
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[[Category: Ho C]]
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[[Category: Oxidoreductase]]
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[[Category: Pratt EA]]

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CRYSTAL STRUCTURE OF D-LACTATE DEHYDROGENASE, A PERIPHERAL MEMBRANE RESPIRATORY ENZYME.

PDB ID 1f0x

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