1r2f

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[[Image:1r2f.png|left|200px]]
 
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{{STRUCTURE_1r2f| PDB=1r2f | SCENE= }}
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==RIBONUCLEOTIDE REDUCTASE R2F PROTEIN FROM SALMONELLA TYPHIMURIUM==
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<StructureSection load='1r2f' size='340' side='right'caption='[[1r2f]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===RIBONUCLEOTIDE REDUCTASE R2F PROTEIN FROM SALMONELLA TYPHIMURIUM===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1r2f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R2F FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9748343}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r2f OCA], [https://pdbe.org/1r2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r2f RCSB], [https://www.ebi.ac.uk/pdbsum/1r2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r2f ProSAT]</span></td></tr>
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[[1r2f]] is a 2 chain structure of [[Ribonucleotide reductase]] with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R2F OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIR4_SALTY RIR4_SALTY] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2F contains the tyrosyl radical required for catalysis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/1r2f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r2f ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Ribonucleotide reductase|Ribonucleotide reductase]]
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009748343</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Category: Eklund H]]
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[[Category: Eklund, H.]]
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[[Category: Eriksson M]]
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[[Category: Eriksson, M.]]
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[[Category: Nucleotide metabolism]]
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[[Category: Oxidoreductase]]
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[[Category: Reductase]]
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Current revision

RIBONUCLEOTIDE REDUCTASE R2F PROTEIN FROM SALMONELLA TYPHIMURIUM

PDB ID 1r2f

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