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1m66

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[[Image:1m66.png|left|200px]]
 
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{{STRUCTURE_1m66| PDB=1m66 | SCENE= }}
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==Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine==
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<StructureSection load='1m66' size='340' side='right'caption='[[1m66]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1m66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M66 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12445769}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCP:2-BROMO-6-CHLORO-PURINE'>BCP</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m66 OCA], [https://pdbe.org/1m66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m66 RCSB], [https://www.ebi.ac.uk/pdbsum/1m66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m66 ProSAT]</span></td></tr>
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[[1m66]] is a 1 chain structure of [[Glycerol-3-Phosphate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M66 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GPDA_LEIME GPDA_LEIME]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m6/1m66_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m66 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Glycerol-3-Phosphate Dehydrogenase|Glycerol-3-Phosphate Dehydrogenase]]
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*[[Glycerol-3-phosphate dehydrogenase 3D structures|Glycerol-3-phosphate dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012445769</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Leishmania mexicana]]
[[Category: Leishmania mexicana]]
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[[Category: Choe, J.]]
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[[Category: Choe J]]
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[[Category: Gelb, M H.]]
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[[Category: Gelb MH]]
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[[Category: Hol, W G.J.]]
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[[Category: Hol WGJ]]
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[[Category: Kennedy, K J.]]
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[[Category: Kennedy KJ]]
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[[Category: Suresh, S.]]
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[[Category: Suresh S]]
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[[Category: Wisedchaisri, G.]]
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[[Category: Wisedchaisri G]]
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[[Category: Nad-binding motif]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine

PDB ID 1m66

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