1iav

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[[Image:1iav.png|left|200px]]
 
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{{STRUCTURE_1iav| PDB=1iav | SCENE= }}
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==STRUCTURE ON NATIVE (ASN 87) SUBTILISIN FROM BACILLUS LENTUS==
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<StructureSection load='1iav' size='340' side='right'caption='[[1iav]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===STRUCTURE ON NATIVE (ASN 87) SUBTILISIN FROM BACILLUS LENTUS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1iav]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lederbergia_lenta Lederbergia lenta]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1c13 1c13]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IAV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10493860}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iav OCA], [https://pdbe.org/1iav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iav RCSB], [https://www.ebi.ac.uk/pdbsum/1iav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iav ProSAT]</span></td></tr>
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[[1iav]] is a 1 chain structure of [[Subtilisin]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_lentus Bacillus lentus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1c13 1c13]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IAV OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SUBS_LEDLE SUBS_LEDLE] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ia/1iav_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iav ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Subtilisin|Subtilisin]]
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*[[Subtilisin 3D structures|Subtilisin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010493860</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Bacillus lentus]]
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[[Category: Lederbergia lenta]]
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[[Category: Subtilisin]]
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[[Category: Bott R]]
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[[Category: Bott, R.]]
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[[Category: Knapp M]]
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[[Category: Knapp, M.]]
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[[Category: Altered flexibility]]
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[[Category: Hydrolase]]
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[[Category: Subtilisin]]
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STRUCTURE ON NATIVE (ASN 87) SUBTILISIN FROM BACILLUS LENTUS

PDB ID 1iav

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