2wbi

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[[Image:2wbi.png|left|200px]]
 
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{{STRUCTURE_2wbi| PDB=2wbi | SCENE= }}
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==Crystal structure of human acyl-CoA dehydrogenase 11==
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<StructureSection load='2wbi' size='340' side='right'caption='[[2wbi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF HUMAN ACYL-COA DEHYDROGENASE 11===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2wbi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBI FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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[[2wbi]] is a 2 chain structure of [[Acyl-CoA dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBI OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbi OCA], [https://pdbe.org/2wbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbi RCSB], [https://www.ebi.ac.uk/pdbsum/2wbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbi ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACD11_HUMAN ACD11_HUMAN] Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA (PubMed:21237683). Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain (Probable).<ref>PMID:21237683</ref> <ref>PMID:21237683</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/2wbi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wbi ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Acyl-CoA dehydrogenase|Acyl-CoA dehydrogenase]]
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*[[Acyl-CoA dehydrogenase 3D structures|Acyl-CoA dehydrogenase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith CH]]
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[[Category: Edwards, A M.]]
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[[Category: Bountra C]]
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[[Category: Guo, K.]]
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[[Category: Edwards AM]]
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[[Category: Muniz, J R.C.]]
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[[Category: Guo K]]
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[[Category: Oppermann, U.]]
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[[Category: Muniz JRC]]
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[[Category: Pilka, E.]]
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[[Category: Oppermann U]]
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[[Category: Roos, A.]]
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[[Category: Pilka E]]
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[[Category: Savitsky, P.]]
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[[Category: Roos A]]
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[[Category: Vondelft, F.]]
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[[Category: Savitsky P]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Yue, W.]]
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[[Category: Yue W]]
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[[Category: Acyl-coa]]
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[[Category: Von Delft F]]
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[[Category: Dehydrogenase]]
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[[Category: Human]]
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[[Category: Oxidoreductase]]
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[[Category: Phosphoprotein]]
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Current revision

Crystal structure of human acyl-CoA dehydrogenase 11

PDB ID 2wbi

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