2qyi

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[[Image:2qyi.png|left|200px]]
 
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{{STRUCTURE_2qyi| PDB=2qyi | SCENE= }}
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==Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin==
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<StructureSection load='2qyi' size='340' side='right'caption='[[2qyi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2qyi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QYI FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16081330}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qyi OCA], [https://pdbe.org/2qyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qyi RCSB], [https://www.ebi.ac.uk/pdbsum/2qyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qyi ProSAT]</span></td></tr>
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[[2qyi]] is a 4 chain structure of [[Chymotrypsin Inhibitor]] and [[Trypsin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QYI OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qy/2qyi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qyi ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Chymotrypsin Inhibitor|Chymotrypsin Inhibitor]]
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*[[Chymotrypsin inhibitor 3D structures|Chymotrypsin inhibitor 3D structures]]
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*[[Trypsin|Trypsin]]
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016081330</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Large Structures]]
[[Category: Psophocarpus tetragonolobus]]
[[Category: Psophocarpus tetragonolobus]]
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[[Category: Dasgupta, J.]]
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[[Category: Dasgupta J]]
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[[Category: Dattagupta, J K.]]
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[[Category: Dattagupta JK]]
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[[Category: Khamrui, S.]]
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[[Category: Khamrui S]]
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[[Category: Sen, U.]]
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[[Category: Sen U]]
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[[Category: Bovine trypsin]]
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[[Category: Complex]]
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[[Category: Digestion]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Metal-binding]]
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[[Category: P1 mutant]]
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[[Category: Protease]]
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[[Category: Protease inhibitor]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Serine protease inhibitor]]
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[[Category: Trypsin inhibitor]]
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[[Category: Zymogen]]
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Current revision

Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin

PDB ID 2qyi

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