2qrf
From Proteopedia
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| - | [[Image:2qrf.png|left|200px]] | ||
| - | + | ==Green Fluorescent Protein: Cyclized-only Intermediate of Chromophore Maturation in the Q183E variant== | |
| - | + | <StructureSection load='2qrf' size='340' side='right'caption='[[2qrf]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2qrf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QRF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZO:[(2R,4S)-2-[(1S,2R)-1-AMINO-2-HYDROXYPROPYL]-2-HYDROXY-4-(4-HYDROXYBENZYL)-5-OXOIMIDAZOLIDIN-1-YL]ACETIC+ACID'>CZO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[2qrf]] is a 1 chain structure | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qrf OCA], [https://pdbe.org/2qrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qrf RCSB], [https://www.ebi.ac.uk/pdbsum/2qrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qrf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qr/2qrf_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qrf ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | + | *[[Green Fluorescent Protein 3D structures|Green Fluorescent Protein 3D structures]] | |
| - | + | __TOC__ | |
| - | *[[Green Fluorescent Protein|Green Fluorescent Protein]] | + | </StructureSection> |
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[[Category: Aequorea victoria]] | [[Category: Aequorea victoria]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Barondeau DP]] |
| - | [[Category: | + | [[Category: Getzoff ED]] |
| - | [[Category: | + | [[Category: Hitomi C]] |
| - | [[Category: | + | [[Category: Tainer JA]] |
| - | [[Category: | + | [[Category: Wood TI]] |
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Current revision
Green Fluorescent Protein: Cyclized-only Intermediate of Chromophore Maturation in the Q183E variant
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