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1piw

From Proteopedia

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[[Image:1piw.png|left|200px]]
 
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{{STRUCTURE_1piw| PDB=1piw | SCENE= }}
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==APO AND HOLO STRUCTURES OF AN NADP(H)-DEPENDENT CINNAMYL ALCOHOL DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE==
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<StructureSection load='1piw' size='340' side='right'caption='[[1piw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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===APO AND HOLO STRUCTURES OF AN NADP(H)-DEPENDENT CINNAMYL ALCOHOL DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1piw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PIW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15289102}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1piw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1piw OCA], [https://pdbe.org/1piw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1piw RCSB], [https://www.ebi.ac.uk/pdbsum/1piw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1piw ProSAT]</span></td></tr>
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[[1piw]] is a 2 chain structure of [[Alcohol dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PIW OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ADH6_YEAST ADH6_YEAST] NADP-dependent alcohol dehydrogenase with a broad substrate specificity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pi/1piw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1piw ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Alcohol dehydrogenase|Alcohol dehydrogenase]]
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*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015289102</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Biosca, J A.]]
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[[Category: Biosca JA]]
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[[Category: Fita, I.]]
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[[Category: Fita I]]
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[[Category: Larroy, C.]]
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[[Category: Larroy C]]
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[[Category: Ochoa, W F.]]
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[[Category: Ochoa WF]]
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[[Category: Pares, X.]]
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[[Category: Pares X]]
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[[Category: Valencia, E.]]
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[[Category: Valencia E]]
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[[Category: Adh topology]]
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[[Category: Oxidoreductase]]
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Current revision

APO AND HOLO STRUCTURES OF AN NADP(H)-DEPENDENT CINNAMYL ALCOHOL DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE

PDB ID 1piw

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