1p0f

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[[Image:1p0f.png|left|200px]]
 
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{{STRUCTURE_1p0f| PDB=1p0f | SCENE= }}
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==Crystal Structure of the Binary Complex: NADP(H)-Dependent Vertebrate Alcohol Dehydrogenase (ADH8) with the cofactor NADP==
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<StructureSection load='1p0f' size='340' side='right'caption='[[1p0f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===Crystal Structure of the Binary Complex: NADP(H)-Dependent Vertebrate Alcohol Dehydrogenase (ADH8) with the cofactor NADP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1p0f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pelophylax_perezi Pelophylax perezi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P0F FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12818203}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0f OCA], [https://pdbe.org/1p0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p0f RCSB], [https://www.ebi.ac.uk/pdbsum/1p0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0f ProSAT]</span></td></tr>
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[[1p0f]] is a 2 chain structure of [[Alcohol dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Pelophylax_perezi Pelophylax perezi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0F OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ADH8_PELPE ADH8_PELPE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/1p0f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p0f ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Alcohol dehydrogenase|Alcohol dehydrogenase]]
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*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012818203</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Pelophylax perezi]]
[[Category: Pelophylax perezi]]
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[[Category: Farres, J.]]
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[[Category: Farres J]]
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[[Category: Fita, I.]]
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[[Category: Fita I]]
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[[Category: Ochoa, W F.]]
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[[Category: Ochoa WF]]
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[[Category: Pares, X.]]
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[[Category: Pares X]]
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[[Category: Rosell, A.]]
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[[Category: Rosell A]]
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[[Category: Valencia, E.]]
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[[Category: Valencia E]]
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[[Category: Adh topology]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of the Binary Complex: NADP(H)-Dependent Vertebrate Alcohol Dehydrogenase (ADH8) with the cofactor NADP

PDB ID 1p0f

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