1nj8
From Proteopedia
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| - | [[Image:1nj8.png|left|200px]] | ||
| - | + | ==Crystal Structure of Prolyl-tRNA Synthetase from Methanocaldococcus janaschii== | |
| - | + | <StructureSection load='1nj8' size='340' side='right'caption='[[1nj8]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1nj8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NJ8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nj8 OCA], [https://pdbe.org/1nj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nj8 RCSB], [https://www.ebi.ac.uk/pdbsum/1nj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nj8 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1nj8]] is a 4 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SYP_METJA SYP_METJA] Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). Can inadvertently accommodate and process non-cognate amino acids such as cysteine and alanine.<ref>PMID:10642548</ref> <ref>PMID:10869184</ref> <ref>PMID:11141055</ref> <ref>PMID:11866507</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nj/1nj8_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nj8 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Aminoacyl tRNA | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Methanocaldococcus jannaschii]] | [[Category: Methanocaldococcus jannaschii]] | ||
| - | + | [[Category: Kamtekar S]] | |
| - | [[Category: Kamtekar | + | [[Category: Kennedy WD]] |
| - | [[Category: Kennedy | + | [[Category: Soll D]] |
| - | [[Category: Soll | + | [[Category: Stathopoulos C]] |
| - | [[Category: Stathopoulos | + | [[Category: Steitz TA]] |
| - | [[Category: Steitz | + | [[Category: Wang J]] |
| - | [[Category: Wang | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Prolyl-tRNA Synthetase from Methanocaldococcus janaschii
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