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1mau

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[[Image:1mau.png|left|200px]]
 
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{{STRUCTURE_1mau| PDB=1mau | SCENE= }}
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==Crystal structure of Tryptophanyl-tRNA Synthetase Complexed with ATP and Tryptophanamide in a Pre-Transition state Conformation==
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<StructureSection load='1mau' size='340' side='right'caption='[[1mau]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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===Crystal structure of Tryptophanyl-tRNA Synthetase Complexed with ATP and Tryptophanamide in a Pre-Transition state Conformation===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1mau]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MAU FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12473451}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LTN:L-TRYPTOPHANAMIDE'>LTN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mau OCA], [https://pdbe.org/1mau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mau RCSB], [https://www.ebi.ac.uk/pdbsum/1mau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mau ProSAT]</span></td></tr>
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[[1mau]] is a 1 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MAU OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYW_GEOSE SYW_GEOSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/1mau_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mau ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012473451</ref><references group="xtra"/>
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[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Tryptophan--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Bricogne, G.]]
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[[Category: Bricogne G]]
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[[Category: Carter, C W.]]
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[[Category: Carter Jr CW]]
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[[Category: Hu, M.]]
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[[Category: Hu M]]
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[[Category: Huang, X.]]
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[[Category: Huang X]]
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[[Category: Ilyin, V.]]
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[[Category: Ilyin V]]
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[[Category: Retailleau, P.]]
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[[Category: Retailleau P]]
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[[Category: Roversi, P.]]
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[[Category: Roversi P]]
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[[Category: Vachette, P.]]
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[[Category: Vachette P]]
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[[Category: Vonrhein, C.]]
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[[Category: Vonrhein C]]
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[[Category: Weinreb, V.]]
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[[Category: Weinreb V]]
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[[Category: Yin, Y.]]
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[[Category: Yin Y]]
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[[Category: Amino-acyl trna synthetase]]
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[[Category: Atp binding site]]
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[[Category: Ligase]]
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[[Category: Pre-transition state]]
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[[Category: Rossmann fold]]
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Current revision

Crystal structure of Tryptophanyl-tRNA Synthetase Complexed with ATP and Tryptophanamide in a Pre-Transition state Conformation

PDB ID 1mau

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