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1g0v

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[[Image:1g0v.png|left|200px]]
 
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{{STRUCTURE_1g0v| PDB=1g0v | SCENE= }}
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==THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT, MVV==
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<StructureSection load='1g0v' size='340' side='right'caption='[[1g0v]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT, MVV===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1g0v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G0V FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11042188}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g0v OCA], [https://pdbe.org/1g0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g0v RCSB], [https://www.ebi.ac.uk/pdbsum/1g0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g0v ProSAT]</span></td></tr>
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[[1g0v]] is a 2 chain structure of [[Pepsin]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0V OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_YEAST CARP_YEAST] Aspartyl protease implicated in the post-translational regulation of S.cerevisiae vacuolar proteinases. Acts on YSCB, on YSCY and on itself.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/1g0v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g0v ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Pepsin|Pepsin]]
*[[Pepsin|Pepsin]]
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*[[Proteinase 3D structures|Proteinase 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:011042188</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Saccharopepsin]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Brownsey, B G.]]
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[[Category: Brownsey BG]]
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[[Category: Bur, D.]]
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[[Category: Bur D]]
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[[Category: Copeland, T.]]
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[[Category: Copeland T]]
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[[Category: Dunn, B M.]]
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[[Category: Dunn BM]]
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[[Category: Gustchina, A.]]
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[[Category: Gustchina A]]
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[[Category: Kay, J.]]
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[[Category: Kay J]]
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[[Category: Lees, W.]]
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[[Category: Lees W]]
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[[Category: Li, M.]]
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[[Category: Li M]]
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[[Category: Phylip, L H.]]
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[[Category: Phylip LH]]
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[[Category: Winther, J.]]
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[[Category: Winther J]]
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[[Category: Wlodawer, A.]]
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[[Category: Wlodawer A]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Mvv]]
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[[Category: Proteinase some]]
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Current revision

THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT, MVV

PDB ID 1g0v

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