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1c4d
From Proteopedia
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| - | [[Image:1c4d.gif|left|200px]]<br /><applet load="1c4d" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1c4d, resolution 2.0Å" /> | ||
| - | '''GRAMICIDIN CSCL COMPLEX'''<br /> | ||
| - | == | + | ==GRAMICIDIN CSCL COMPLEX== |
| - | + | <StructureSection load='1c4d' size='340' side='right'caption='[[1c4d]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1c4d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_brevis Brevibacillus brevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C4D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C4D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=FVA:N-FORMYL-L-VALINE'>FVA</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=PRD_000150:GRAMICIDIN+A'>PRD_000150</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c4d OCA], [https://pdbe.org/1c4d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c4d RCSB], [https://www.ebi.ac.uk/pdbsum/1c4d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c4d ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | <div style="background-color:#fffaf0;"> | |
| - | + | == Publication Abstract from PubMed == | |
| - | + | Gramicidin, a linear polypeptide composed of hydrophobic amino acids with alternating L- and D- configurations, forms transmembrane ion channels. The crystal structure of a gramicidin-cesium complex has been determined at 2.0 angstrom resolution. In this structure, gramicidin forms a 26 angstrom long tube comprised of two polypeptide chains arranged as antiparallel beta strands that are wrapped into a left-handed helical coil with 6.4 residues per turn. The polypeptide backbone forms the interior of the hydrophilic, solvent-filled pore and the side chains form a hydrophobic and relatively regular surface on the outside of the pore. This example of a crystal structure of a solvent-filled ion pore provides a basis for understanding the physical nature of ion translocation. | |
| - | + | ||
| - | + | ||
| - | + | The gramicidin pore: crystal structure of a cesium complex.,Wallace BA, Ravikumar K Science. 1988 Jul 8;241(4862):182-7. PMID:2455344<ref>PMID:2455344</ref> | |
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 1c4d" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Gramicidin|Gramicidin]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Brevibacillus brevis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wallace BA]] | ||
Current revision
GRAMICIDIN CSCL COMPLEX
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