This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3nhw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:00, 14 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3nhw.png|left|200px]]
 
-
{{STRUCTURE_3nhw| PDB=3nhw | SCENE= }}
+
==X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2==
-
 
+
<StructureSection load='3nhw' size='340' side='right'caption='[[3nhw]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-
===X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3nhw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NHW FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_19265439}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ZXZ:1,4-DIMETHYLQUINOLIN-2(1H)-ONE'>ZXZ</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nhw OCA], [https://pdbe.org/3nhw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nhw RCSB], [https://www.ebi.ac.uk/pdbsum/3nhw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nhw ProSAT]</span></td></tr>
-
[[3nhw]] is a 2 chain structure of [[Quinone reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NHW OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
==See Also==
==See Also==
-
*[[Quinone reductase|Quinone reductase]]
+
*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:019265439</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Sturdy, M.]]
+
[[Category: Large Structures]]
-
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+
[[Category: Sturdy M]]
-
[[Category: Protein dimer]]
+

Current revision

X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2

PDB ID 3nhw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3nhw"
Personal tools