3n0t

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[[Image:3n0t.png|left|200px]]
 
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{{STRUCTURE_3n0t| PDB=3n0t | SCENE= }}
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==Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A==
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<StructureSection load='3n0t' size='340' side='right'caption='[[3n0t]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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===Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3n0t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N0T FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OPY:(3S)-4-OXO-4-PIPERIDIN-1-YLBUTANE-1,3-DIAMINE'>OPY</scene></td></tr>
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[[3n0t]] is a 4 chain structure of [[Dipeptidyl peptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0t OCA], [https://pdbe.org/3n0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n0t RCSB], [https://www.ebi.ac.uk/pdbsum/3n0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n0t ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPP2_HUMAN DPP2_HUMAN] Plays an important role in the degradation of some oligopeptides.<ref>PMID:15487984</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/3n0t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n0t ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
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*[[Dipeptidyl peptidase 3D structures|Dipeptidyl peptidase 3D structures]]
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[[Category: Dipeptidyl-peptidase II]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Bochkarev A]]
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[[Category: Cossar, D.]]
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[[Category: Bountra C]]
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[[Category: Crombet, L.]]
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[[Category: Cossar D]]
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[[Category: Dobrovetsky, E.]]
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[[Category: Crombet L]]
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[[Category: Edwards, A M.]]
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[[Category: Dobrovetsky E]]
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[[Category: Haffner, C.]]
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[[Category: Edwards AM]]
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[[Category: Hassell, A.]]
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[[Category: Haffner C]]
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[[Category: Khutoreskaya, G.]]
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[[Category: Hassell A]]
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[[Category: Pagannon, S.]]
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[[Category: Khutoreskaya G]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Pagannon S]]
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[[Category: Seitova, A.]]
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[[Category: Seitova A]]
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[[Category: Shewchuk, L.]]
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[[Category: Shewchuk L]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Aminopeptidase]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Cytoplasmic vesicle]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Lysosome]]
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[[Category: Protease]]
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[[Category: Serine protease]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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[[Category: Zymogen]]
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Current revision

Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A

PDB ID 3n0t

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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