1pis

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[[Image:1pis.png|left|200px]]
 
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{{STRUCTURE_1pis| PDB=1pis | SCENE= }}
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==SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2==
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<StructureSection load='1pis' size='340' side='right'caption='[[1pis]]' scene=''>
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===SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1pis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PIS FirstGlance]. <br>
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{{ABSTRACT_PUBMED_7556053}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pis OCA], [https://pdbe.org/1pis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pis RCSB], [https://www.ebi.ac.uk/pdbsum/1pis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pis ProSAT]</span></td></tr>
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[[1pis]] is a 1 chain structure of [[Phospholipase A2]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PIS OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PA21B_PIG PA21B_PIG] PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pi/1pis_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pis ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phospholipase A2|Phospholipase A2]]
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:007556053</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Berg, B D.Van Den.]]
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[[Category: Boelens R]]
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[[Category: Boelens, R.]]
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[[Category: De Haas GH]]
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[[Category: Haas, G H.De.]]
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[[Category: Kaptein R]]
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[[Category: Kaptein, R.]]
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[[Category: Tessari M]]
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[[Category: Tessari, M.]]
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[[Category: Van Den Berg BD]]
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[[Category: Verheij, H M.]]
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[[Category: Verheij HM]]
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[[Category: Carboxylic ester hydrolase]]
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[[Category: Phosphatide-2-acyl-hydrolase]]
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[[Category: Phospholipase a2]]
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[[Category: Pla2]]
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Current revision

SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2

PDB ID 1pis

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