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1p3h
From Proteopedia
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| - | [[Image:1p3h.png|left|200px]] | ||
| - | + | ==Crystal Structure of the Mycobacterium tuberculosis chaperonin 10 tetradecamer== | |
| - | + | <StructureSection load='1p3h' size='340' side='right'caption='[[1p3h]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1p3h]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jh2 1jh2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3h OCA], [https://pdbe.org/1p3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3h RCSB], [https://www.ebi.ac.uk/pdbsum/1p3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3h ProSAT]</span></td></tr> |
| - | [[1p3h]] is a 14 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CH10_MYCTU CH10_MYCTU] Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.[HAMAP-Rule:MF_00580] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/1p3h_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p3h ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Chaperonin|Chaperonin]] | + | *[[Chaperonin 3D structures|Chaperonin 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Coates | + | [[Category: Coates ARM]] |
| - | [[Category: Coker | + | [[Category: Coker AR]] |
| - | [[Category: Fossati | + | [[Category: Fossati G]] |
| - | [[Category: Mascagni | + | [[Category: Mascagni P]] |
| - | [[Category: Roberts | + | [[Category: Roberts MM]] |
| - | + | [[Category: Wood SP]] | |
| - | [[Category: Wood | + | |
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Current revision
Crystal Structure of the Mycobacterium tuberculosis chaperonin 10 tetradecamer
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