1lwx

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[[Image:1lwx.png|left|200px]]
 
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{{STRUCTURE_1lwx| PDB=1lwx | SCENE= }}
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==AZT DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE==
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<StructureSection load='1lwx' size='340' side='right'caption='[[1lwx]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===AZT DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lwx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LWX FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9207061}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZD:3-AZIDO-3-DEOXYTHYMIDINE-5-DIPHOSPHATE'>AZD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lwx OCA], [https://pdbe.org/1lwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lwx RCSB], [https://www.ebi.ac.uk/pdbsum/1lwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lwx ProSAT]</span></td></tr>
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[[1lwx]] is a 3 chain structure of [[Nucleoside diphosphate kinase]] with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LWX OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NDKC_DICDI NDKC_DICDI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lw/1lwx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lwx ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
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*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009207061</ref><references group="xtra"/>
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[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
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[[Category: Nucleoside-diphosphate kinase]]
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[[Category: Large Structures]]
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[[Category: Janin, J.]]
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[[Category: Janin J]]
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[[Category: Xu, Y.]]
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[[Category: Xu Y]]
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[[Category: Antiviral agent]]
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[[Category: Azidothymidine]]
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[[Category: Phosphotransferase]]
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Current revision

AZT DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE

PDB ID 1lwx

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