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3ah5

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[[Image:3ah5.png|left|200px]]
 
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{{STRUCTURE_3ah5| PDB=3ah5 | SCENE= }}
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==Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP==
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<StructureSection load='3ah5' size='340' side='right'caption='[[3ah5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ah5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AH5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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[[3ah5]] is a 6 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AH5 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ah5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ah5 OCA], [https://pdbe.org/3ah5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ah5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ah5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ah5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/THYX_HELPY THYX_HELPY] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.
==See Also==
==See Also==
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*[[Thymidylate synthase|Thymidylate synthase]]
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*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
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[[Category: Helicobacter pylori]]
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__TOC__
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[[Category: Hu, Y.]]
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</StructureSection>
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[[Category: Wang, D.]]
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[[Category: Helicobacter pylori 26695]]
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[[Category: Zhang, J.]]
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[[Category: Large Structures]]
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[[Category: Zhang, X.]]
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[[Category: Hu Y]]
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[[Category: Zou, Q.]]
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[[Category: Wang D]]
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[[Category: Dump]]
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[[Category: Zhang J]]
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[[Category: Fad]]
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[[Category: Zhang X]]
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[[Category: Helicobacter pylori]]
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[[Category: Zou Q]]
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[[Category: Thyx]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP

PDB ID 3ah5

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