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1pem
From Proteopedia
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| - | [[Image:1pem.png|left|200px]] | ||
| - | + | ==Ribonucleotide Reductase Protein R1E from Salmonella typhimurium== | |
| - | + | <StructureSection load='1pem' size='340' side='right'caption='[[1pem]], [[Resolution|resolution]] 2.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1pem]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PEM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pem OCA], [https://pdbe.org/1pem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pem RCSB], [https://www.ebi.ac.uk/pdbsum/1pem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pem ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1pem]] is a 1 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/RIR3_SALTY RIR3_SALTY] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1E contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pe/1pem_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pem ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Ribonucleotide reductase|Ribonucleotide reductase]] | + | *[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | [[Category: Salmonella enterica subsp. enterica serovar | + | [[Category: Eklund H]] |
| - | [[Category: Eklund | + | [[Category: Eliasson R]] |
| - | [[Category: Eliasson | + | [[Category: Farnegardh M]] |
| - | [[Category: Farnegardh | + | [[Category: Jordan A]] |
| - | [[Category: Jordan | + | [[Category: Uhlin U]] |
| - | [[Category: Uhlin | + | [[Category: Uppsten M]] |
| - | [[Category: Uppsten | + | |
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Current revision
Ribonucleotide Reductase Protein R1E from Salmonella typhimurium
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