1ks3
From Proteopedia
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| - | [[Image:1ks3.png|left|200px]] | ||
| - | + | ==METHIONINE CORE MUTANT OF T4 LYSOZYME== | |
| - | + | <StructureSection load='1ks3' size='340' side='right'caption='[[1ks3]], [[Resolution|resolution]] 2.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ks3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KS3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ks3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ks3 OCA], [https://pdbe.org/1ks3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ks3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ks3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ks3 ProSAT]</span></td></tr> |
| - | [[1ks3]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/1ks3_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ks3 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Lysozyme 3D structures|Lysozyme 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia virus T4]] |
| - | [[Category: Baase | + | [[Category: Large Structures]] |
| - | [[Category: Busam | + | [[Category: Baase WA]] |
| - | [[Category: Gassner | + | [[Category: Busam RD]] |
| - | [[Category: Lindstrom | + | [[Category: Gassner NC]] |
| - | [[Category: Matthews | + | [[Category: Lindstrom JD]] |
| - | [[Category: Mooers | + | [[Category: Matthews BW]] |
| - | [[Category: Quillin | + | [[Category: Mooers BH]] |
| - | [[Category: Weaver | + | [[Category: Quillin ML]] |
| - | + | [[Category: Weaver LH]] | |
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Current revision
METHIONINE CORE MUTANT OF T4 LYSOZYME
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