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1d0d

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[[Image:1d0d.png|left|200px]]
 
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{{STRUCTURE_1d0d| PDB=1d0d | SCENE= }}
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==CRYSTAL STRUCTURE OF TICK ANTICOAGULANT PROTEIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR==
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<StructureSection load='1d0d' size='340' side='right'caption='[[1d0d]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF TICK ANTICOAGULANT PROTEIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1d0d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Ornithodoros_moubata Ornithodoros moubata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D0D FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10716178}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d0d OCA], [https://pdbe.org/1d0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d0d RCSB], [https://www.ebi.ac.uk/pdbsum/1d0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d0d ProSAT]</span></td></tr>
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[[1d0d]] is a 2 chain structure of [[Basic Pancreatic Trypsin Inhibitor]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Ornithodoros_moubata Ornithodoros moubata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D0D OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TAP_ORNMO TAP_ORNMO] TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d0/1d0d_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d0d ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Basic Pancreatic Trypsin Inhibitor|Basic Pancreatic Trypsin Inhibitor]]
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*[[BPTI 3D structures|BPTI 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010716178</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Large Structures]]
[[Category: Ornithodoros moubata]]
[[Category: Ornithodoros moubata]]
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[[Category: Arni, R V.]]
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[[Category: Arni RV]]
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[[Category: Padmanabhan, K.]]
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[[Category: Padmanabhan K]]
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[[Category: Padmanabhan, K P.]]
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[[Category: Padmanabhan KP]]
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[[Category: St Charles, R.]]
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[[Category: StCharles R]]
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[[Category: Tulinsky, A.]]
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[[Category: Tulinsky A]]
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[[Category: Blood clotting inhibitor]]
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[[Category: Factor xa inhibitor]]
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[[Category: Kunitz inhibitor]]
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Current revision

CRYSTAL STRUCTURE OF TICK ANTICOAGULANT PROTEIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR

PDB ID 1d0d

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