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3q23

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[[Image:3q23.png|left|200px]]
 
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{{STRUCTURE_3q23| PDB=3q23 | SCENE= }}
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==X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II==
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<StructureSection load='3q23' size='340' side='right'caption='[[3q23]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3q23]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_N4 Escherichia virus N4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q23 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21321236}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2HP:DIHYDROGENPHOSPHATE+ION'>2HP</scene>, <scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q23 OCA], [https://pdbe.org/3q23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q23 RCSB], [https://www.ebi.ac.uk/pdbsum/3q23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q23 ProSAT]</span></td></tr>
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[[3q23]] is a 4 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_phage_n4 Escherichia phage n4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q23 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RPOLV_BPN4 RPOLV_BPN4] DNA-dependent RNA polymerase, which is injected into the host upon infection and transcribes the phage early genes from promoters that have a 5-bp stem-3 nt loop hairpin structure.<ref>PMID:18362338</ref> <ref>PMID:19061645</ref>
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021321236</ref><references group="xtra"/>
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__TOC__
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[[Category: DNA-directed RNA polymerase]]
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</StructureSection>
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[[Category: Escherichia phage n4]]
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[[Category: Escherichia virus N4]]
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[[Category: Gleghorn, M L.]]
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[[Category: Large Structures]]
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[[Category: Murakami, K S.]]
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[[Category: Gleghorn ML]]
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[[Category: De novo transcription initiation]]
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[[Category: Murakami KS]]
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[[Category: Dna-hairpin]]
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[[Category: Gmpcpp]]
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[[Category: Gpcpp]]
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[[Category: Initiation complex]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Phosphate ion]]
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[[Category: Protein-dna complex]]
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[[Category: Rna polymerase]]
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[[Category: Transferase-dna complex]]
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[[Category: Two-metal catalysis]]
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[[Category: Virion rna polymerase]]
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Current revision

X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with GMPCPP and Manganese: sustrate complex II

PDB ID 3q23

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