This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2r8o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2r8o" [edit=sysop:move=sysop])
Current revision (09:20, 21 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2r8o.png|left|200px]]
 
-
{{STRUCTURE_2r8o| PDB=2r8o | SCENE= }}
+
==Transketolase from E. coli in complex with substrate D-xylulose-5-phosphate==
-
 
+
<StructureSection load='2r8o' size='340' side='right'caption='[[2r8o]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
-
===Transketolase from E. coli in complex with substrate D-xylulose-5-phosphate===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2r8o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R8O FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_17914867}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=T5X:2-C-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-(2-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-2-YL}-5-O-PHOSPHONO-D-XYLITOL'>T5X</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8o OCA], [https://pdbe.org/2r8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r8o RCSB], [https://www.ebi.ac.uk/pdbsum/2r8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8o ProSAT]</span></td></tr>
-
[[2r8o]] is a 2 chain structure of [[Transketolase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8O OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TKT1_ECOLI TKT1_ECOLI] Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate. Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.<ref>PMID:17914867</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r8o_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r8o ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
*[[Transketolase|Transketolase]]
*[[Transketolase|Transketolase]]
-
 
+
*[[Transketolase 3D structures|Transketolase 3D structures]]
-
==Reference==
+
== References ==
-
<ref group="xtra">PMID:017914867</ref><references group="xtra"/>
+
<references/>
-
[[Category: Escherichia coli k12]]
+
__TOC__
-
[[Category: Transketolase]]
+
</StructureSection>
-
[[Category: Asztalos, P.]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Tittmann, K.]]
+
[[Category: Large Structures]]
-
[[Category: Weiss, M S.]]
+
[[Category: Asztalos P]]
-
[[Category: Wille, G.]]
+
[[Category: Tittmann K]]
-
[[Category: Metal-binding]]
+
[[Category: Weiss MS]]
-
[[Category: Reaction intermediate]]
+
[[Category: Wille G]]
-
[[Category: Thiamine pyrophosphate]]
+
-
[[Category: Transferase]]
+

Current revision

Transketolase from E. coli in complex with substrate D-xylulose-5-phosphate

PDB ID 2r8o

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2r8o"
Personal tools