2wj8
From Proteopedia
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| - | [[Image:2wj8.png|left|200px]] | ||
| - | + | ==Respiratory Syncitial Virus RiboNucleoProtein== | |
| - | + | <StructureSection load='2wj8' size='340' side='right'caption='[[2wj8]], [[Resolution|resolution]] 3.29Å' scene=''> | |
| - | === | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[2wj8]] is a 40 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)] and [https://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus_A_strain_Long Human respiratory syncytial virus A strain Long]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJ8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.29Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BO4:BORATE+ION'>BO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wj8 OCA], [https://pdbe.org/2wj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wj8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wj8 ProSAT]</span></td></tr> |
| - | [[2wj8]] is a 40 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NCAP_HRSVA NCAP_HRSVA] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.<ref>PMID:9299631</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wj8_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wj8 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Nucleoprotein|Nucleoprotein]] | + | *[[Laminin|Laminin]] |
| - | + | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |
| - | == | + | == References == |
| - | < | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Bedouelle | + | [[Category: Human respiratory syncytial virus A strain Long]] |
| - | [[Category: Bhella | + | [[Category: Large Structures]] |
| - | [[Category: Bricogne | + | [[Category: Bedouelle H]] |
| - | [[Category: Castagne | + | [[Category: Bhella D]] |
| - | [[Category: Damier-Piolle | + | [[Category: Bricogne G]] |
| - | [[Category: Duquerroy | + | [[Category: Castagne N]] |
| - | [[Category: Eleouet | + | [[Category: Damier-Piolle L]] |
| - | [[Category: | + | [[Category: Duquerroy S]] |
| - | [[Category: Rey | + | [[Category: Eleouet J]] |
| - | [[Category: Tawar | + | [[Category: MacLellan K]] |
| - | [[Category: Varela | + | [[Category: Rey FA]] |
| - | [[Category: Vonrhein | + | [[Category: Tawar RG]] |
| - | + | [[Category: Varela PF]] | |
| - | + | [[Category: Vonrhein C]] | |
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Current revision
Respiratory Syncitial Virus RiboNucleoProtein
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