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1f3f

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[[Image:1f3f.png|left|200px]]
 
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{{STRUCTURE_1f3f| PDB=1f3f | SCENE= }}
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==STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX==
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<StructureSection load='1f3f' size='340' side='right'caption='[[1f3f]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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===STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1f3f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F3F FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10899107}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D4D:2,3-DEHYDRO-2,3-DEOXY-THYMIDINE+5-DIPHOSPHATE'>D4D</scene>, <scene name='pdbligand=D4T:2,3-DEHYDRO-2,3-DEOXY-THYMIDINE+5-TRIPHOSPHATE'>D4T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f3f OCA], [https://pdbe.org/1f3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f3f RCSB], [https://www.ebi.ac.uk/pdbsum/1f3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f3f ProSAT]</span></td></tr>
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[[1f3f]] is a 3 chain structure of [[Nucleoside diphosphate kinase]] with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F3F OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NDKC_DICDI NDKC_DICDI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/1f3f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f3f ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
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*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010899107</ref><references group="xtra"/>
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[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
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[[Category: Nucleoside-diphosphate kinase]]
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[[Category: Large Structures]]
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[[Category: Boretto, J.]]
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[[Category: Boretto J]]
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[[Category: Canard, B.]]
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[[Category: Canard B]]
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[[Category: Deville-Bonne, D.]]
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[[Category: Deville-Bonne D]]
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[[Category: Guerreiro, C.]]
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[[Category: Guerreiro C]]
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[[Category: Janin, J.]]
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[[Category: Janin J]]
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[[Category: Meyer, P.]]
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[[Category: Meyer P]]
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[[Category: Sarfati, S.]]
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[[Category: Sarfati S]]
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[[Category: Schneider, B.]]
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[[Category: Schneider B]]
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[[Category: Veron, M.]]
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[[Category: Veron M]]
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[[Category: Anti-hiv nucleoside analogue]]
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[[Category: Ch...o bond]]
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[[Category: Nucleoside diphosphate kinase]]
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[[Category: Phosphorylation]]
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[[Category: Transferase]]
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Current revision

STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX

PDB ID 1f3f

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