This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3i5v

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3i5v" [edit=sysop:move=sysop])
Current revision (06:39, 3 April 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3i5v.png|left|200px]]
 
-
{{STRUCTURE_3i5v| PDB=3i5v | SCENE= }}
+
==Crystal structure of beta toxin 275-280 from Staphylococcus aureus==
-
 
+
<StructureSection load='3i5v' size='340' side='right'caption='[[3i5v]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-
===Crystal structure of beta toxin 275-280 from Staphylococcus aureus===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3i5v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_RN4220 Staphylococcus aureus subsp. aureus RN4220]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I5V FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_17873030}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5v OCA], [https://pdbe.org/3i5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i5v RCSB], [https://www.ebi.ac.uk/pdbsum/3i5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5v ProSAT]</span></td></tr>
-
[[3i5v]] is a 4 chain structure of [[Hemolysin]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5V OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PHLC_STAAU PHLC_STAAU] Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i5v_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i5v ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Hemolysin|Hemolysin]]
+
*[[Hemolysin 3D structures|Hemolysin 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:017873030</ref><references group="xtra"/>
+
[[Category: Large Structures]]
-
[[Category: Staphylococcus aureus]]
+
[[Category: Staphylococcus aureus subsp. aureus RN4220]]
-
[[Category: Huseby, M.]]
+
[[Category: Huseby M]]
-
[[Category: Kruse, A C.]]
+
[[Category: Kruse AC]]
-
[[Category: Ohlendorf, D H.]]
+
[[Category: Ohlendorf DH]]
-
[[Category: Shi, K.]]
+
[[Category: Shi K]]
-
[[Category: Beta toxin]]
+
-
[[Category: Hemolysin]]
+
-
[[Category: Sphingomyelinase]]
+
-
[[Category: Toxin]]
+

Current revision

Crystal structure of beta toxin 275-280 from Staphylococcus aureus

PDB ID 3i5v

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3i5v"
Personal tools