3hxp

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[[Image:3hxp.png|left|200px]]
 
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{{STRUCTURE_3hxp| PDB=3hxp | SCENE= }}
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==Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577==
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<StructureSection load='3hxp' size='340' side='right'caption='[[3hxp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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===Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3hxp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HXP FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[3hxp]] is a 1 chain structure of [[ABC transporter]] and [[FhuD]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXP OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hxp OCA], [https://pdbe.org/3hxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hxp RCSB], [https://www.ebi.ac.uk/pdbsum/3hxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hxp ProSAT], [https://www.topsan.org/Proteins/NESGC/3hxp TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FHUD_BACSU FHUD_BACSU] Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen.<ref>PMID:8388528</ref> <ref>PMID:16672620</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/3hxp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hxp ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[ABC transporter|ABC transporter]]
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*[[ABC transporter 3D structures|ABC transporter 3D structures]]
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*[[FhuD|FhuD]]
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*[[Ferric hydroxamate uptake receptor|Ferric hydroxamate uptake receptor]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Acton, T B.]]
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[[Category: Large Structures]]
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[[Category: Chen,C X.]]
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[[Category: Acton TB]]
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[[Category: Cunningham,K.]]
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[[Category: Chen CX]]
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[[Category: Everett, J K.]]
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[[Category: Cunningham K]]
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[[Category: Fang,F.]]
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[[Category: Everett JK]]
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[[Category: Forouhar,F.]]
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[[Category: Fang F]]
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[[Category: Hunt,J F.]]
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[[Category: Forouhar F]]
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[[Category: Ma,L.]]
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[[Category: Hunt JF]]
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[[Category: Montelione, G T.]]
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[[Category: Ma L]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Nair, R.]]
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[[Category: Nair R]]
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[[Category: Neely, H.]]
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[[Category: Neely H]]
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[[Category: Rost, B.]]
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[[Category: Rost B]]
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[[Category: Seetharaman, J.]]
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[[Category: Seetharaman J]]
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[[Category: Tong,L.]]
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[[Category: Tong L]]
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[[Category: Xiao,R.]]
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[[Category: Xiao R]]
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[[Category: Alpha-beta protein]]
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[[Category: Cell membrane]]
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[[Category: Ion transport]]
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[[Category: Iron]]
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[[Category: Iron transport]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Palmitate]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Transport]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577

PDB ID 3hxp

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