2frs

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[[Image:2frs.png|left|200px]]
 
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{{STRUCTURE_2frs| PDB=2frs | SCENE= }}
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==Crystal structure of the f15w mutant of apo-cellular retinoic acid binding protein type ii at 1.51 angstroms resolution==
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<StructureSection load='2frs' size='340' side='right'caption='[[2frs]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
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===Crystal structure of the f15w mutant of apo-cellular retinoic acid binding protein type ii at 1.51 angstroms resolution===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2frs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FRS FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16979656}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2frs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2frs OCA], [https://pdbe.org/2frs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2frs RCSB], [https://www.ebi.ac.uk/pdbsum/2frs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2frs ProSAT]</span></td></tr>
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[[2frs]] is a 2 chain structure of [[CRABP I ( Cellular Retinoic Acid Binding Protein )]], [[Cellular retinoic acid-binding protein]], [[Gustavo Elberto Epalza Sanchez/Sandbox 1]] and [[Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein)]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FRS OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/2frs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2frs ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[CRABP I ( Cellular Retinoic Acid Binding Protein )|CRABP I ( Cellular Retinoic Acid Binding Protein )]]
*[[CRABP I ( Cellular Retinoic Acid Binding Protein )|CRABP I ( Cellular Retinoic Acid Binding Protein )]]
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*[[Cellular retinoic acid-binding protein|Cellular retinoic acid-binding protein]]
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*[[Cellular retinoic acid-binding protein 3D structures|Cellular retinoic acid-binding protein 3D structures]]
*[[Gustavo Elberto Epalza Sanchez/Sandbox 1|Gustavo Elberto Epalza Sanchez/Sandbox 1]]
*[[Gustavo Elberto Epalza Sanchez/Sandbox 1|Gustavo Elberto Epalza Sanchez/Sandbox 1]]
*[[Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein)|Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein)]]
*[[Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein)|Molecular Playground/CRABP I (Cellular Retinoic Acid Binding Protein)]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016979656</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Geiger, J H.]]
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[[Category: Large Structures]]
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[[Category: Vaezeslami, S.]]
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[[Category: Geiger JH]]
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[[Category: Beta barrel]]
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[[Category: Vaezeslami S]]
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[[Category: Crabpii]]
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[[Category: High resolution]]
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[[Category: Mutant]]
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[[Category: Retinoic acid]]
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[[Category: Retinoid]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of the f15w mutant of apo-cellular retinoic acid binding protein type ii at 1.51 angstroms resolution

PDB ID 2frs

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