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3ga2
From Proteopedia
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| - | [[Image:3ga2.png|left|200px]] | ||
| - | + | ==Crystal structure of the Endonuclease_V (BSU36170) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR624== | |
| - | + | <StructureSection load='3ga2' size='340' side='right'caption='[[3ga2]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3ga2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GA2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | == | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nfi, ywqL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr> |
| - | [[3ga2]] is a 1 chain structure | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Deoxyribonuclease_V Deoxyribonuclease V], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.7 3.1.21.7] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ga2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga2 OCA], [https://pdbe.org/3ga2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ga2 RCSB], [https://www.ebi.ac.uk/pdbsum/3ga2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga2 ProSAT], [https://www.topsan.org/Proteins/NESGC/3ga2 TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/NFI_BACSU NFI_BACSU]] Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga2_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ga2 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Endonuclease|Endonuclease]] | + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Vibrio subtilis ehrenberg 1835]] | ||
[[Category: Deoxyribonuclease V]] | [[Category: Deoxyribonuclease V]] | ||
| - | [[Category: Abashidze, M | + | [[Category: Large Structures]] |
| - | [[Category: Acton, T B | + | [[Category: Abashidze, M]] |
| - | [[Category: Cunningham, K | + | [[Category: Acton, T B]] |
| - | [[Category: Everett, J K | + | [[Category: Cunningham, K]] |
| - | [[Category: Fang, Y | + | [[Category: Everett, J K]] |
| - | [[Category: Forouhar, F | + | [[Category: Fang, Y]] |
| - | [[Category: Hunt, J F | + | [[Category: Forouhar, F]] |
| - | [[Category: Hussain, M | + | [[Category: Hunt, J F]] |
| - | [[Category: Janjua, H | + | [[Category: Hussain, M]] |
| - | [[Category: Ma, L | + | [[Category: Janjua, H]] |
| - | [[Category: Montelione, G T | + | [[Category: Ma, L C]] |
| - | [[Category: | + | [[Category: Montelione, G T]] |
| - | [[Category: Nair, R | + | [[Category: Structural genomic]] |
| - | [[Category: Owens, L | + | [[Category: Nair, R]] |
| - | [[Category: Rost, B | + | [[Category: Owens, L]] |
| - | [[Category: Seetharaman, J | + | [[Category: Rost, B]] |
| - | [[Category: Tong, L | + | [[Category: Seetharaman, J]] |
| - | [[Category: Wang, D | + | [[Category: Tong, L]] |
| - | [[Category: Xiao, R | + | [[Category: Wang, D]] |
| + | [[Category: Xiao, R]] | ||
[[Category: Alpha-beta protein]] | [[Category: Alpha-beta protein]] | ||
| + | [[Category: Cytoplasm]] | ||
[[Category: Dna damage]] | [[Category: Dna damage]] | ||
[[Category: Dna repair]] | [[Category: Dna repair]] | ||
| Line 39: | Line 56: | ||
[[Category: Magnesium]] | [[Category: Magnesium]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
| - | [[Category: Northeast structural genomics consortium]] | ||
[[Category: Nuclease]] | [[Category: Nuclease]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the Endonuclease_V (BSU36170) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR624
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Categories: Vibrio subtilis ehrenberg 1835 | Deoxyribonuclease V | Large Structures | Abashidze, M | Acton, T B | Cunningham, K | Everett, J K | Fang, Y | Forouhar, F | Hunt, J F | Hussain, M | Janjua, H | Ma, L C | Montelione, G T | Structural genomic | Nair, R | Owens, L | Rost, B | Seetharaman, J | Tong, L | Wang, D | Xiao, R | Alpha-beta protein | Cytoplasm | Dna damage | Dna repair | Endonuclease | Hydrolase | Magnesium | Nesg | Nuclease | PSI, Protein structure initiative
