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3iy8

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[[Image:3iy8.png|left|200px]]
 
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{{STRUCTURE_3iy8| PDB=3iy8 | SCENE= }}
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==Leishmania tarentolae Mitonchondrial Ribosome small subunit==
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<SX load='3iy8' size='340' side='right' viewer='molstar' caption='[[3iy8]], [[Resolution|resolution]] 14.10&Aring;' scene=''>
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===Leishmania tarentolae Mitonchondrial Ribosome small subunit===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3iy8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IY8 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19497863}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iy8 OCA], [https://pdbe.org/3iy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iy8 RCSB], [https://www.ebi.ac.uk/pdbsum/3iy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iy8 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3iy8]] is a 11 chain structure of [[Ribosomal protein S11]], [[Ribosomal protein S12]], [[Ribosomal protein S15]], [[Ribosomal protein S16]], [[Ribosomal protein S17]], [[Ribosomal protein S18]], [[Ribosomal protein S5]], [[Ribosomal protein S6]], [[Ribosomal protein S8]] and [[Ribosomal protein S9]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IY8 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/RS5_ECOLI RS5_ECOLI] With S4 and S12 plays an important role in translational accuracy. Many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).<ref>PMID:15652481</ref> Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<ref>PMID:15652481</ref> The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp.<ref>PMID:15652481</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/3iy8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iy8 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Ribosomal protein S17|Ribosomal protein S17]]
*[[Ribosomal protein S17|Ribosomal protein S17]]
*[[Ribosomal protein S18|Ribosomal protein S18]]
*[[Ribosomal protein S18|Ribosomal protein S18]]
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*[[Ribosomal protein S5|Ribosomal protein S5]]
 
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*[[Ribosomal protein S6|Ribosomal protein S6]]
 
*[[Ribosomal protein S8|Ribosomal protein S8]]
*[[Ribosomal protein S8|Ribosomal protein S8]]
*[[Ribosomal protein S9|Ribosomal protein S9]]
*[[Ribosomal protein S9|Ribosomal protein S9]]
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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==Reference==
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== References ==
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<ref group="xtra">PMID:019497863</ref><references group="xtra"/>
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<references/>
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[[Category: Escherichia coli]]
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__TOC__
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[[Category: Leishmania tarentolae]]
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</SX>
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[[Category: Agrawal, R K.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Booth, T M.]]
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[[Category: Large Structures]]
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[[Category: Maslov, D A.]]
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[[Category: Sharma, M R.]]
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[[Category: Simpson, L.]]
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[[Category: Antibiotic resistance]]
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[[Category: Cryoem]]
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[[Category: Endonuclease]]
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[[Category: Hydrolase]]
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[[Category: Leishmania tarentolae]]
[[Category: Leishmania tarentolae]]
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[[Category: Methylation]]
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[[Category: Agrawal RK]]
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[[Category: Minimal rna.]]
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[[Category: Booth TM]]
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[[Category: Mitochondrial ribosome]]
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[[Category: Maslov DA]]
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[[Category: Nuclease]]
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[[Category: Sharma MR]]
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[[Category: Repressor]]
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[[Category: Simpson L]]
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[[Category: Ribonucleoprotein]]
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[[Category: Ribosomal protein]]
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[[Category: Ribosome]]
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[[Category: Rna-binding]]
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[[Category: Rrna-binding]]
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[[Category: Translation regulation]]
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[[Category: Trna-binding]]
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Current revision

Leishmania tarentolae Mitonchondrial Ribosome small subunit

3iy8, resolution 14.10Å

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