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1mc2

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[[Image:1mc2.png|left|200px]]
 
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{{STRUCTURE_1mc2| PDB=1mc2 | SCENE= }}
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==monomeric LYS-49 phospholipase A2 homologue purified from AG==
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<StructureSection load='1mc2' size='340' side='right'caption='[[1mc2]], [[Resolution|resolution]] 0.85&Aring;' scene=''>
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===monomeric LYS-49 phospholipase A2 homologue purified from AG===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1mc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MC2 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12871974}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mc2 OCA], [https://pdbe.org/1mc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mc2 RCSB], [https://www.ebi.ac.uk/pdbsum/1mc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mc2 ProSAT]</span></td></tr>
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[[1mc2]] is a 1 chain structure of [[Phospholipase A2]] with sequence from [http://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MC2 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PA2H_DEIAC PA2H_DEIAC] Snake venom phospholipase A2 homolog that shows myotoxic activity. Lacks both catalytic and direct hemolytic activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/1mc2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mc2 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phospholipase A2|Phospholipase A2]]
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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*[[Phospholipase A2 homolog|Phospholipase A2 homolog]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012871974</ref><ref group="xtra">PMID:018754631</ref><references group="xtra"/>
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</StructureSection>
[[Category: Deinagkistrodon acutus]]
[[Category: Deinagkistrodon acutus]]
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[[Category: Huang, Q Q.]]
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[[Category: Large Structures]]
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[[Category: Jelsch, C.]]
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[[Category: Huang QQ]]
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[[Category: Liu, Q.]]
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[[Category: Jelsch C]]
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[[Category: Niu, L W.]]
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[[Category: Liu Q]]
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[[Category: Teng, M K.]]
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[[Category: Niu LW]]
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[[Category: Weeks, C M.]]
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[[Category: Teng MK]]
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[[Category: Zhang, R G.]]
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[[Category: Weeks CM]]
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[[Category: Agkistrodon acutus]]
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[[Category: Zhang RG]]
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[[Category: Snake venom]]
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[[Category: Toxin]]
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[[Category: Ys49-phospholipase a2]]
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Current revision

monomeric LYS-49 phospholipase A2 homologue purified from AG

PDB ID 1mc2

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OCA

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