This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3rkk
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3rkk.png|left|200px]] | ||
| - | + | ==Crystal Structure of New Delhi Metallo-Beta-Lactamase-1 from Klebsiella pneumoniae== | |
| - | + | <StructureSection load='3rkk' size='340' side='right'caption='[[3rkk]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3rkk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RKK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rkk OCA], [https://pdbe.org/3rkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rkk RCSB], [https://www.ebi.ac.uk/pdbsum/3rkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rkk ProSAT]</span></td></tr> |
| - | [[3rkk]] is a 2 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | ||
==See Also== | ==See Also== | ||
| - | *[[Beta-lactamase|Beta-lactamase]] | + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
[[Category: Klebsiella pneumoniae]] | [[Category: Klebsiella pneumoniae]] | ||
| - | [[Category: Babnigg | + | [[Category: Large Structures]] |
| - | [[Category: Binkowski | + | [[Category: Babnigg G]] |
| - | [[Category: Jedrzejczak | + | [[Category: Binkowski TA]] |
| - | [[Category: Joachimiak | + | [[Category: Jedrzejczak R]] |
| - | [[Category: Kim | + | [[Category: Joachimiak A]] |
| - | + | [[Category: Kim Y]] | |
| - | + | [[Category: Sacchettini J]] | |
| - | [[Category: Sacchettini | + | [[Category: Tesar C]] |
| - | [[Category: Tesar | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of New Delhi Metallo-Beta-Lactamase-1 from Klebsiella pneumoniae
| |||||||||||
