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1rxh

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[[Image:1rxh.png|left|200px]]
 
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{{STRUCTURE_1rxh| PDB=1rxh | SCENE= }}
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==Crystal structure of streptavidin mutant L124R (M1) complexed with biotinyl p-nitroanilide (BNI)==
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<StructureSection load='1rxh' size='340' side='right'caption='[[1rxh]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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===Crystal structure of streptavidin mutant L124R (M1) complexed with biotinyl p-nitroanilide (BNI)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1rxh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RXH FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15079055}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNI:5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC+ACID+(4-NITRO-PHENYL)-AMIDE'>BNI</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxh OCA], [https://pdbe.org/1rxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rxh RCSB], [https://www.ebi.ac.uk/pdbsum/1rxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rxh ProSAT]</span></td></tr>
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[[1rxh]] is a 2 chain structure of [[Avidin]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXH OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rx/1rxh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rxh ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Avidin|Avidin]]
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*[[Avidin 3D structures|Avidin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015079055</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
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[[Category: Bayer, E A.]]
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[[Category: Bayer EA]]
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[[Category: Eisenberg-Domovich, Y.]]
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[[Category: Eisenberg-Domovich Y]]
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[[Category: Livnah, O.]]
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[[Category: Livnah O]]
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[[Category: Nir, O.]]
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[[Category: Nir O]]
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[[Category: Pazy, Y.]]
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[[Category: Pazy Y]]
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[[Category: Raboy, B.]]
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[[Category: Raboy B]]
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[[Category: Wilchek, M.]]
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[[Category: Wilchek M]]
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[[Category: Avidin]]
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[[Category: Pseudo enzymatic activity]]
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[[Category: Streptavidin]]
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[[Category: Unknown function]]
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Current revision

Crystal structure of streptavidin mutant L124R (M1) complexed with biotinyl p-nitroanilide (BNI)

PDB ID 1rxh

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