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1rea

From Proteopedia

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[[Image:1rea.png|left|200px]]
 
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{{STRUCTURE_1rea| PDB=1rea | SCENE= }}
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==STRUCTURE OF THE RECA PROTEIN-ADP COMPLEX==
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<StructureSection load='1rea' size='340' side='right'caption='[[1rea]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===STRUCTURE OF THE RECA PROTEIN-ADP COMPLEX===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1rea]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The April 2014 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''RecA and Rad51'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2014_4 10.2210/rcsb_pdb/mom_2014_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1REA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1REA FirstGlance]. <br>
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{{ABSTRACT_PUBMED_1731253}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rea OCA], [https://pdbe.org/1rea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rea RCSB], [https://www.ebi.ac.uk/pdbsum/1rea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rea ProSAT]</span></td></tr>
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[[1rea]] is a 1 chain structure of [[Recombinase A]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1REA OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RECA_ECOLI RECA_ECOLI] Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.[HAMAP-Rule:MF_00268]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/re/1rea_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rea ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Recombinase A|Recombinase A]]
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*[[3D structures of recombinase A|3D structures of recombinase A]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:001731253</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Steitz, T A.]]
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[[Category: Large Structures]]
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[[Category: Story, R M.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Dna binding protein]]
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[[Category: RecA and Rad51]]
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[[Category: Homologous recombination]]
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[[Category: Steitz TA]]
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[[Category: Self-cleavage stimulation]]
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[[Category: Story RM]]

Current revision

STRUCTURE OF THE RECA PROTEIN-ADP COMPLEX

PDB ID 1rea

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