3cw4

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[[Image:3cw4.png|left|200px]]
 
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{{STRUCTURE_3cw4| PDB=3cw4 | SCENE= }}
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==Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2==
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<StructureSection load='3cw4' size='340' side='right'caption='[[3cw4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3cw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus Influenza A virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CW4 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19144639}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cw4 OCA], [https://pdbe.org/3cw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cw4 RCSB], [https://www.ebi.ac.uk/pdbsum/3cw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cw4 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3cw4]] is a 1 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW4 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019144639</ref><references group="xtra"/>
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[[Category: Influenza A virus]]
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[[Category: Influenza a virus]]
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[[Category: Large Structures]]
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[[Category: Fujiki, H.]]
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[[Category: Fujiki H]]
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[[Category: Horita, T.]]
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[[Category: Horita T]]
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[[Category: Kise, D.]]
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[[Category: Kise D]]
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[[Category: Kuzuhara, T.]]
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[[Category: Kuzuhara T]]
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[[Category: Murasaki, Y.]]
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[[Category: Murasaki Y]]
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[[Category: Tsuge, H.]]
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[[Category: Tsuge H]]
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[[Category: Utsunomiya, H.]]
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[[Category: Utsunomiya H]]
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[[Category: Yoshida, H.]]
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[[Category: Yoshida H]]
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[[Category: Mitochondrion]]
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[[Category: Mrna capping]]
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[[Category: Mrna processing]]
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[[Category: Nucleus]]
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[[Category: Rna polymerase]]
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[[Category: Transferase]]
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[[Category: Virion]]
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Current revision

Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2

PDB ID 3cw4

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