2jkv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:53, 13 December 2023) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2jkv.png|left|200px]]
 
-
{{STRUCTURE_2jkv| PDB=2jkv | SCENE= }}
+
==Structure of human Phosphogluconate Dehydrogenase in complex with NADPH at 2.53A==
-
 
+
<StructureSection load='2jkv' size='340' side='right'caption='[[2jkv]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
-
===STRUCTURE OF HUMAN PHOSPHOGLUCONATE DEHYDROGENASE IN COMPLEX WITH NADPH AT 2.53A===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2jkv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JKV FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.532&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[2jkv]] is a 6 chain structure of [[6-phosphogluconate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKV OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkv OCA], [https://pdbe.org/2jkv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jkv RCSB], [https://www.ebi.ac.uk/pdbsum/2jkv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jkv ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/2jkv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jkv ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[6-phosphogluconate dehydrogenase|6-phosphogluconate dehydrogenase]]
+
*[[6-phosphogluconate dehydrogenase 3D structures|6-phosphogluconate dehydrogenase 3D structures]]
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Bountra, C.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Delft, F Von.]]
+
[[Category: Bountra C]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Guo, K.]]
+
[[Category: Guo K]]
-
[[Category: Kavanagh, K L.]]
+
[[Category: Kavanagh KL]]
-
[[Category: Muniz, J R.C.]]
+
[[Category: Muniz JRC]]
-
[[Category: Murray, J.]]
+
[[Category: Murray J]]
-
[[Category: Oppermann, U.]]
+
[[Category: Oppermann U]]
-
[[Category: Picaud, S.]]
+
[[Category: Picaud S]]
-
[[Category: Pilka, E S.]]
+
[[Category: Pilka ES]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Dehydrogenase]]
+
[[Category: Von Delft F]]
-
[[Category: Nadp]]
+
-
[[Category: Nadph]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Pentose shunt]]
+
-
[[Category: Phosphogluconate]]
+

Current revision

Structure of human Phosphogluconate Dehydrogenase in complex with NADPH at 2.53A

PDB ID 2jkv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2jkv"
Personal tools