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4ajn

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[[Image:4ajn.png|left|200px]]
 
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{{STRUCTURE_4ajn| PDB=4ajn | SCENE= }}
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==rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)-3-oxo-propyl)carbamoylamino)ethyl)phenyl)methyl) propanedioic acid==
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<StructureSection load='4ajn' size='340' side='right'caption='[[4ajn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)-3-oxo-propyl)carbamoylamino)ethyl)phenyl)methyl) propanedioic acid===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ajn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AJN FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22417091}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=88V:(4-{2-[({3-[(2-METHYL-1,3-BENZOTHIAZOL-6-YL)AMINO]-3-OXOPROPYL}CARBAMOYL)AMINO]ETHYL}BENZYL)PROPANEDIOIC+ACID'>88V</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ajn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajn OCA], [https://pdbe.org/4ajn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ajn RCSB], [https://www.ebi.ac.uk/pdbsum/4ajn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajn ProSAT]</span></td></tr>
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[[4ajn]] is a 4 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJN OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LDHA_RAT LDHA_RAT]
==See Also==
==See Also==
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*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:022417091</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: L-lactate dehydrogenase]]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Brassington, C.]]
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[[Category: Brassington C]]
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[[Category: Caputo, A.]]
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[[Category: Caputo A]]
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[[Category: Davies, G.]]
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[[Category: Davies G]]
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[[Category: Hassall, G.]]
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[[Category: Hassall G]]
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[[Category: Pearson, S.]]
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[[Category: Pearson S]]
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[[Category: Tart, J.]]
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[[Category: Tart J]]
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[[Category: Tucker, J A.]]
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[[Category: Tucker JA]]
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[[Category: Ward, R.]]
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[[Category: Ward R]]
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[[Category: Watson, M.]]
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[[Category: Watson M]]
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[[Category: Fragment based lead generated inhibitor]]
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[[Category: Oxidoreductase-inhibitor complex]]
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Current revision

rat LDHA in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)-3-oxo-propyl)carbamoylamino)ethyl)phenyl)methyl) propanedioic acid

PDB ID 4ajn

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