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1lwl

From Proteopedia

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[[Image:1lwl.png|left|200px]]
 
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{{STRUCTURE_1lwl| PDB=1lwl | SCENE= }}
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==Crystal Structure of Cytochrome P450-cam with a Fluorescent Probe D-8-Ad (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-octyl-amide)==
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<StructureSection load='1lwl' size='340' side='right'caption='[[1lwl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===Crystal Structure of Cytochrome P450-cam with a Fluorescent Probe D-8-Ad (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-octyl-amide)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1lwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LWL FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12197708}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DSO:ADAMANTANE-1-CARBOXYLIC+ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE'>DSO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lwl OCA], [https://pdbe.org/1lwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lwl RCSB], [https://www.ebi.ac.uk/pdbsum/1lwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lwl ProSAT]</span></td></tr>
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[[1lwl]] is a 1 chain structure of [[Cytochrome P450]] with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LWL OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CPXA_PSEPU CPXA_PSEPU] Involved in a camphor oxidation system.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lw/1lwl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lwl ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cytochrome P450|Cytochrome P450]]
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012197708</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Camphor 5-monooxygenase]]
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[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
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[[Category: Chiu, R.]]
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[[Category: Chiu R]]
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[[Category: Dunn, A R.]]
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[[Category: Dunn AR]]
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[[Category: Goodin, D B.]]
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[[Category: Goodin DB]]
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[[Category: Gray, H B.]]
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[[Category: Gray HB]]
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[[Category: Hays, A M.]]
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[[Category: Hays AM]]
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[[Category: Stout, C D.]]
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[[Category: Stout CD]]
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[[Category: Winkler, J R.]]
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[[Category: Winkler JR]]
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[[Category: Adamantane]]
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[[Category: Channel]]
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[[Category: Dansyl]]
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[[Category: Electron transfer]]
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[[Category: Energy transfer]]
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[[Category: Monooxygenase]]
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[[Category: Oxidoreductase]]
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[[Category: Substrate-binding]]
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Current revision

Crystal Structure of Cytochrome P450-cam with a Fluorescent Probe D-8-Ad (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-octyl-amide)

PDB ID 1lwl

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