1ayi
From Proteopedia
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| - | [[Image:1ayi.png|left|200px]] | ||
| - | + | ==COLICIN E7 IMMUNITY PROTEIN IM7== | |
| - | + | <StructureSection load='1ayi' size='340' side='right'caption='[[1ayi]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ayi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AYI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ayi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ayi OCA], [https://pdbe.org/1ayi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ayi RCSB], [https://www.ebi.ac.uk/pdbsum/1ayi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ayi ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1ayi]] is a 1 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ay/1ayi_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ayi ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Colicin | + | *[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Dennis | + | [[Category: Large Structures]] |
| - | [[Category: James | + | [[Category: Dennis CA]] |
| - | [[Category: Kleanthous | + | [[Category: James R]] |
| - | [[Category: Moore | + | [[Category: Kleanthous C]] |
| - | [[Category: Pauptit | + | [[Category: Moore GR]] |
| - | [[Category: Wallis | + | [[Category: Pauptit RA]] |
| - | + | [[Category: Wallis R]] | |
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Current revision
COLICIN E7 IMMUNITY PROTEIN IM7
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