1dpn

[[Image:1dpn.gif|left|200px]]<br /><applet load="1dpn" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1dpn, resolution 0.95&Aring;" />

'''B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE'''<br />

==Overview==

We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.

 

==About this Structure==

1DPN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPN OCA].

 

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10699842 10699842]

[[Category: Protein complex]]

[[Category: An, H.]]

[[Category: Cook, P Dan.]]

[[Category: Egli, M.]]

[[Category: Joachimiak, A.]]

[[Category: Maier, M A.]]

[[Category: Manoharan, M.]]

[[Category: Miller, R.]]

[[Category: Minasov, G.]]

[[Category: Sanishvili, R.]]

[[Category: Teplova, M.]]

[[Category: Tereshko, V.]]

[[Category: Weeks, C M.]]