1hlp

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[[Image:1hlp.png|left|200px]]
 
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{{STRUCTURE_1hlp| PDB=1hlp | SCENE= }}
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==STRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUM==
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<StructureSection load='1hlp' size='340' side='right'caption='[[1hlp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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===STRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUM===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1hlp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HLP FirstGlance]. <br>
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{{ABSTRACT_PUBMED_17812611}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hlp OCA], [https://pdbe.org/1hlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hlp RCSB], [https://www.ebi.ac.uk/pdbsum/1hlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hlp ProSAT]</span></td></tr>
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[[1hlp]] is a 2 chain structure of [[Johnson sandbox 1]] and [[Malate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLP OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MDH_HALMA MDH_HALMA] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/1hlp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hlp ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Johnson sandbox 1|Johnson sandbox 1]]
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*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
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*[[Malate dehydrogenase|Malate dehydrogenase]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:017812611</ref><references group="xtra"/>
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[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
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[[Category: Malate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Dym, O.]]
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[[Category: Dym O]]
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[[Category: Mevarech, M.]]
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[[Category: Mevarech M]]
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[[Category: Sussman, J L.]]
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[[Category: Sussman JL]]
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[[Category: Dehydrogenase]]
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[[Category: Halophilic]]
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Current revision

STRUCTURAL FEATURES STABILIZING HALOPHILIC MALATE DEHYDROGENASE FROM AN ARCHAEBACTERIUM

PDB ID 1hlp

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