1ffn

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[[Image:1ffn.png|left|200px]]
 
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{{STRUCTURE_1ffn| PDB=1ffn | SCENE= }}
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==CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M)==
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<StructureSection load='1ffn' size='340' side='right'caption='[[1ffn]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ffn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FFN FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12218131}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ffn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffn OCA], [https://pdbe.org/1ffn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ffn RCSB], [https://www.ebi.ac.uk/pdbsum/1ffn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffn ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1ffn]] is a 6 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFN OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/1ffn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ffn ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[Major histocompatibility complex|Major histocompatibility complex]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC I 3D structures|MHC I 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:012218131</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Collins, E J.]]
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[[Category: Collins EJ]]
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[[Category: Frelinger, J A.]]
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[[Category: Frelinger JA]]
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[[Category: Maile, R.]]
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[[Category: Maile R]]
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[[Category: Saad, M.]]
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[[Category: Saad M]]
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[[Category: Sharma, A.]]
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[[Category: Sharma A]]
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[[Category: Wang, B.]]
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[[Category: Wang B]]
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[[Category: Immune system-signaling protein complex]]
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[[Category: Major histocompatibility complex]]
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[[Category: Peptide binding]]
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[[Category: T cell receptor]]
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Current revision

CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M)

PDB ID 1ffn

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