This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2f58

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2f58" [edit=sysop:move=sysop])
Current revision (06:25, 3 April 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2f58.png|left|200px]]
 
-
{{STRUCTURE_2f58| PDB=2f58 | SCENE= }}
+
==IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)==
-
 
+
<StructureSection load='2f58' size='340' side='right'caption='[[2f58]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-
===IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2f58]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F58 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_10368281}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARN:1-IMINO-5-PENTANONE'>ARN</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f58 OCA], [https://pdbe.org/2f58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f58 RCSB], [https://www.ebi.ac.uk/pdbsum/2f58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f58 ProSAT]</span></td></tr>
-
[[2f58]] is a 3 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F58 OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KV3AE_MOUSE KV3AE_MOUSE]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/2f58_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f58 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Antibody|Antibody]]
+
*[[Antibody 3D structures|Antibody 3D structures]]
-
 
+
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
-
==Reference==
+
__TOC__
-
<ref group="xtra">PMID:010368281</ref><references group="xtra"/>
+
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Cabezas, E.]]
+
[[Category: Cabezas E]]
-
[[Category: Profy, A T.]]
+
[[Category: Profy AT]]
-
[[Category: Satterthwait, A C.]]
+
[[Category: Satterthwait AC]]
-
[[Category: Stanfield, R L.]]
+
[[Category: Stanfield RL]]
-
[[Category: Stura, E A.]]
+
[[Category: Stura EA]]
-
[[Category: Wilson, I A.]]
+
[[Category: Wilson IA]]
-
[[Category: Fab]]
+
-
[[Category: Gp120]]
+
-
[[Category: Hiv-1]]
+
-
[[Category: Immune system]]
+
-
[[Category: Immunoglobulin]]
+
-
[[Category: V3]]
+

Current revision

IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)

PDB ID 2f58

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools